CV of Tanya Kirilova Kadiyska- Petrova, PhD

EDUCATION AND QUALIFICATIONS:

12.2000 –  PhD Student in Chemistry and Biochemistry- Laboratory of Molecular Pathology and Preclinical University Center – Medical University, Sofia
1996 – 1998 MSc  - Faculty of Biology, Sofia University "St. Kliment Ochridski" and Laboratory of Molecular Pathology, Medical University, Sofia; MSc thesis: “TPH gene and affective disorders: association and linkage study”; Supervisor - Prof. Dr Ivo Kremensky, MD, PhD
1996 – 1998  Specialization - “Clinical Biochemistry”, Department of Biochemistry, Faculty of Biology, Sofia University "St. Kliment Ochridski"
1993 – 1995 BSc - Faculty of Biology, Sofia University "St. Kliment Ochridski"
1986 – 1991 French Language School, Sofia, Bulgaria
 

PROFESSIONAL / RESEARCH EXPERIENCE:

1998 – 2000 Research Assistant, Laboratory of Molecular Pathology, University Hospital of Obstetrics and Gynecology, Medical University – Sofia
03- 08. 2001 Department of Histology and Embryology, Medical Faculty, Namur, Belgium
 

PARTICIPATION IN RESEARCH PROJECTS:

2003 – 2004 Association study for the role of polymorphisms in vitamin D and estrogen receptor type alpha-genes in patients with colorectal carcinoma.- Medical University – Sofia. PI Tanya Kadiyska
2002 – 2005 Investigation of the clinical and pathomorphological characteristics of the hereditary and sporadic colorectal cancer - funded by National Science Fund- Bulgaria. Project Coordinator- Prof. Damyan Damyanov
2002 – 2003 Investigation of the molecular genetics and clinical profiles in Bulgarian HNPCC patients - - funded by National Science Fund- Bulgaria. Project Coordinator- Prof. Damyan Damyanov
2001 – 2003 Investigation of promoter methylation of MLH1 and MSH2 genes on the microsatellite instability in colorectal cancer, funded by National Science Fund- Bulgaria. Principal Investigator- Tanya Petrova
2001 – 2001 Investigation for Microsatellite Instability in colorectal cancer patients, Council of Medical Science, Medical University – Sofia. Principal Investigator: Dr Alexey Savov, PhD
1999 – 2002 Investigation of the possibilities for molecular diagnosis and prophylactics of hereditary colorectal cancer in Bulgaria”, funded by National Science Fund- Bulgaria. Project Coordinator- Prof. Damyan Damyanov
1997 – 2000 Molecular Geneticist in the European collaborative study on molecular genetics in Affective Disorders BIOMED 2 program of the EC (Genes in Affective Disorder). Project Coordinator – Prof. J. Mendlewicz.

INTERNATIONAL COURSES AND CONGRESSES:

  • Grant from the European Society of Human Genetics to attend the 10th International Congress of Human Genetics 2001 in Vienna, Austria
  • 13 th Course in Medical Genetics, Sestri Levante (Genoa)- Grand Hotel dei Castelli
    March 26- April 1, 2000
  • 2th Course in Bioinformatics, Bologna University residential Centre
    November 14-18, 2001

RESEARCH INTERESTS AND SKILLS:

Neuropsychiatric Genetics

  • Extraction and purification of DNA, PCR techniques, Polymorphic DNA markers analysis, SSCA, Electrophoretic separation of DNA fragments, DNA sequencing and genotyping, DNA visualization methods, Gene mapping.
  • Linkage Analysis and Association Study on candidate genes for Affective Disorders;

Cancer Genetics

  • Molecular diagnostic methods in colorectal cancer- Analysis for Microsatellite Instability and Loss of Heterozygosity; Hypermethylation and DNA sequencing of the MMR genes

Cell Biology

  • Signaling Pathways in Human Epidermal Keratinocytes- mechanisms of proliferation and differentiation in cell cultures
  • Cell culturing and treatments, Immunofluorescent labeling methods, Fluorescent and Electron microscopy, Northern blot, Western blot